Actually, the opposite. Milk thistle could offer some potential benefit for endo symptoms. A study conducted in 2022 concluded that silymarin (the main compound in Milk Thistle) can be considered as a feasible option for treatment of women with endometrioma-associated symptoms and according to the study has few side effects*. Silymarin, has powerful antioxidant properties and can help combat free radicals. It also shows promise in reducing fibrosis. This suggests it could be a viable option for treating symptoms associated with endometriosis in women. However, it’s important to note that although this study did not find side effects, in general milk thistle may cause some adverse effects in sensitive people. These can include gastrointestinal issues like nausea and diarrhea, headaches, skin reactions.