Yes, pain that is worse on one side during endometriosis flare-ups can potentially affect your posture and muscles over time. Dealing with endometriosis-related pain often causes you to hunch over or tighten the muscles in response to discomfort. This can lead to cyclical or ongoing back and/or pelvic pain due to the strain placed on one side of the body. When you consistently favor one side, it can cause muscle imbalances, poor posture, and stiffness. However, there are ways to manage this discomfort. One of the best approaches is incorporating moderate physical activity into your routine, such as yoga, Pilates, walking, or swimming. Not only can these activities help alleviate endometriosis symptoms, but they also promote balanced muscle function, improve joint mobility, and enhance overall well-being. Physical activity can also help correct posture and prevent further muscle tension caused by hunching during flare-ups.