Yes it can. There numerous factors that be attributed to changes in appetite and hunger with endo – they often compound on each other. These are: 1.Inflammation: Chronic inflammation associated with endo can affect hormones such as leptin and ghrelin, which regulate appetite, potentially causing a feeling of never getting full and constant hunger. 2. Hormonal Imbalance: Endometriosis is influenced by hormonal fluctuations, particularly estrogen. These hormonal changes can disrupt the body's hunger signals, resulting in constant hunger. 3. Pain and Discomfort: Pain associated with endometriosis can affect appetite regulation. Some woman may experience increased hunger as a coping mechanism for managing pain or discomfort. 4. Medications: Certain medications prescribed for managing endometriosis symptoms, such as hormonal treatments, may influence appetite and metabolism, leading to changes in hunger levels. 5. Psychological Factors: Living with a chronic condition like endometriosis can contribute to stress, anxiety, or depression, which may affect appetite regulation and lead to constant hunger. And we mustn’t forget that Gastrointestinal issues common in endo can cause digestive issues, such as nausea and constipation, which may affect hunger. It's important to note that individual experiences with endometriosis can vary, and not everyone will experience increased hunger as a symptom. Consulting with a healthcare provider can help identify the underlying causes and develop an appropriate management plan.